Neurogenesis

Neurogenesis is the birth of new neurons from neural stem or progenitor cells in the brain. It was long considered that the number of neurons was fixed and they did not replicate after maturity of the brain. It wasn’t until the 1990’s that neurogenesis was observed in the brains of humans, other primates and a number of other species that led to its widespread scientific acceptance.

The term neurogenesis is made up of the words “neuro” meaning “relating to nerves” and “genesis” meaning the formation of something. The term therefore refers to the growth and development of neurons. This process is most active while a baby is developing in the womb and is responsible for the pr The development of new neurons continues during adulthood in two regions of the brain. Neurogenesis takes place in the subventricular zone (SVZ) that forms the lining of the lateral ventricles and the subgranular zone that forms part of the dentate gyrus of the hippocampus area. The SVZ is the site where neuroblasts are formed, which migrate via the rostral migratory stream to the olfactory bulb. Many of these neuroblasts die shortly after they are generated. However, some go on to be functional in the tissue of the brain.oduction of the brain’s neurons.

Keywords: Progenitor cells | Subventricular Zone | Neuroblasts | Olfactory bulb | Rostral migrartory stream.

  • Neonatal stage
  • Neural Stem cell
  • Adult Neurogenesis
  • Progenitor Cells
  • Competent and Committed cells

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