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Eva Kudova

Eva Kudova

Associate Professor
Institute of Organic Chemistry and Biochemistry Czech Academy of Sciences
Czech Republic

Biography

Eva Kudova has been working at the Institute of Organic Chemistry and Biochemistry in Prague, Czech Academy of Sciences (IOCB) since 2002. She completed her PhD in 2009 from Charles University in Prague. Then, she spent 2 years in the lab of Douglas F. Covey, Washington University School of Medicine in St. Louis, Missouri, USA. Since 2011, she works at the IOCB as the project PI at Targeted Research Group of Steroidal Inhibitors. Her main focus of interest is steroidal chemistry, she has been working in this field for more than 10 years. Her major avenue of investigation is design and synthesis of new neuroactive steroidal compounds and structure-activity relationship studies affording NMDARs ligands. Also, she and her colleagues have proposed screening pipeline that should serve as a screening platform for neuroactive steroids targeting CNS diseases and showing neurosteroids´ drug-likeness.

Research Interest

organic synthesis of steroid and steroid-like compounds - NMDA receptors modulators - structure-activity relationship study - central nervous system disorders that are related to NMDA/steroids - early stage drug development